Missing Microbes and Increased Antibiotic Resistance

Missing Microbes and Increased Antibiotic Resistance

Dr. Martin Blaser’s book Missing Microbes details his observations and hypotheses on how overuse and misuse of antibiotics may be the source of modern non-communicable diseases, such as diabetes, asthma, and obesity. The maps of the U.S. colored with obesity and antibiotic prescriptions fit extremely well – and centered on my Southern homeland. Could it be that the obesity epidemic, diabetes, allergies, asthma, and other non-communicable diseases that are centered over the American South are not due to our preference for all things fried or sopped in butter and washed down with a swig of sweet tea? It’s not just due to sitting in front of screens too much. Certainly poor diet and little exercise don’t help. But could an over-use of antibiotics also be to blame?  That was the hypothesis. Obesity Caused by Over Use of Antibiotics? Dr. Martin Blaser from NYU’s experimental research on mice demonstrated drastic changes in the different types of gut bacteria present before and after antibiotic use. More strikingly, when the antibiotic use was discontinued and the bacterial populations rebounded, the bacterial types that did come back were different metabolically. Antibiotics drastically effected the gut microbiome. Does antibiotic somehow set us on a path